High prevalence of polycystic ovary syndrome in women with mild hirsutism and no other significant clinical symptoms.
نویسندگان
چکیده
OBJECTIVE To verify the conclusions of the Endocrine Society Guidelines that patients with mild hirsutism and no other important clinical signs (menstrual irregularities, infertility, central obesity, acanthosis nigricans, rapid progression of the hirsutism, clitoromegaly) should not be further studied. DESIGN Retrospective study in patients referred because of mild hirsutism and no other clinical signs. SETTING Department of Clinical Medicine of the University of Palermo. PATIENT(S) One hundred fifty-two patients with mild hirsutism. INTERVENTION(S) Measurement of serum testosterone, dehydroepiandrosterone sulfate, 17-OH-Progesterone, assessment of ovulation by measurement of progesterone in 21 to 24 days and ovarian ultrasound. RESULT(S) In 72 (47%) patients a diagnosis of polycyctic ovarian syndrome (PCOS) was performed. Polycyctic ovarian syndrome patients included 56 patients with the mild ovulatory form (OV-PCOS) but also 16 patients with the anovulatory form (classic PCOS). Three (2%) patients had nonclassic adrenal hyperplasia. CONCLUSION(S) Because of the high prevalence of PCOS and the possibility of finding nonclassic 21-hydroxylase deficiency, patients with mild hirsutism need a diagnostic evaluation that should include 17-hydroxyprogesterone measurement plus assessment of ovulation and ovarian ultrasound.
منابع مشابه
Prevalence and hormonal profile of polycystic ovary syndrome in young Kashmiri women presenting with hirsutism: A hospital based study
Background: Hirsutism, a common clinical condition, not onlycauses cosmetic concern but may also be a sign of underlyingdisease. Polycystic ovary syndrome (PCOS) is an importantand common cause of hirsutism. In fact, many women withPCOS present as hirsutism. This study assessed young Kashmiriwomen presenting as hirsutism, for ultrasonographic evidence ofpolycystic ovaries (PCO), in addition to ...
متن کاملOnm-4: A Simple Screening Approach for Assessing Prevalence and Clinical Characteristics of Polycystic Ovary Syndrome among Students of Babol Universities in Iran
Background: Studies have revealed that polycystic ovary syndrome (PCOS) usually begins in adolescence, and it might manifest differently in different populations. In Iran, prevalence and phenotypes of PCOS among women in the community are unknown. The aim of the study was to estimate prevalence and clinical characteristics of Polycystic Ovary Syndrome in a community setting in Iran in 2013-2014...
متن کاملOnm-3: Health Related Quality of Life in Women with Polycystic Ovary Syndrome (PCOS
Background: Polycystic ovary syndrome (PCOS) is a disorder of hyperandrogenemia and chronic anovulation which affects 5-10% of all women. The PCOS symptoms such as hirsutism, irregular menses, obesity and infertility are a major source of psychological morbidity and can negatively affect quality of life. In this study, we examined the health-related quality of life among Iranian women who suffe...
متن کاملP-182: The Comparison of Clinical and Laboratory Characteristics in Obese and Normal Weight Women with Polycystic Ovary Syndrome
Background: The main characteristic of polycystic ovary syndrome (PCOS) is oligomenorrhea with clinical and biochemical signs of hyperandrogenism(HA) and the phenotypic spectrum of PCOS is very broad. There are very limited studies about the features of patients with PCOS in Iran. The purpose of this study is to compare the clinical and laboratory characteristics of PCOS between the overweight ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Fertility and sterility
دوره 94 1 شماره
صفحات -
تاریخ انتشار 2010